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Scientific Associate III, Computational Biologist

September 26 2021
Industries Education, Training , Healthcare, social assistance
Categories Biological, Life Sciences, Genetics, Clinical data, Statistics, Biostatistics, Pharma, Biotech, Pharma, Biotech, Sciences, R&D
Toronto, ON

Job Posting #869302

Position: Scientific Associate III, Computational Biology
Site: Princess Margaret Cancer Centre
Department: Research
Reports to: Principal Investigator
Salary: $39.05 - $48.81 per hours (Commensurate with experience and consistent with UHN Compensation Policy)
Hours: 37.5 hour per week
Status: Permanent Full-time

University Health Network (UHN) is looking for an experienced Scientific Associate III in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a network of research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN's five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

A Temporary full-time position is available in Toronto, at the Princess Margaret Cancer Centre, University Health Network. The successful candidate will be supervised by Dr. Gary Bader and will support bioinformatics/computational biology efforts of the principal investigators in our Princess Margaret Cancer Center stem cell group. The stem cell group represents a diverse and world class group of scientists studying stemness in the context of both normal and malignant development. The successful candidate will be integrated into 2-3 labs and will support development, analysis, and interpretation of results from: RNA-seq, scRNA-Seq, Chip-Seq, mi-RNA seq, whole genome sequencing, and chromatin conformation capture.

Candidates must have a PhD or higher degree with strong biology expertise and experience in computer science, bioinformatics and biostatistics/statistics as well as hands-on experience in the use of Unix/Linux command line, R, and statistical approaches (including Machine Learning techniques) to analyze, visualize and interpret genome-scale data sets. Preferred but not required are expertise in a scripting language (Python, Perl), best practices for software development (e.g. version control) and the use of high-performance computing systems (e.g. TORQUE) for analyzing large data sets. Hands-on experience processing and analyzing next-generation sequencing data, ATAC-seq and RNA-Sequencing data analysis is preferred. Experience with single cell sequencing data (e.g. Fluidigm C1, 10X, Dropseq) and tools (e.g. Seurat, SCONE, SINGuLAR) is a strong plus. Experience with the basic principles of cellular processes and cancer biology will be considered a strength.
Candidates should have a strong sense of teamwork, be highly motivated, possess excellent organizational, problem-solving and communication skills (both verbal and written). Applicants are expected to have published in the field of computational biology will be Excellent salary and benefits will be provided.


  • At minimum, a PhD is required in Biology, Computer Science, Bioinformatics or equivalent
  • At minimum, 5 years of related research experience
  • Experience in computational biology
  • Experience in fostering collaborations between diverse research and clinical groups
  • Effective communication (written and verbal), problem-solving and consensus building skills
  • Excellent organization, interpersonal and time management skills
  • Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code

Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

If you are interested, please attach your complete academic curriculum vitae (CV), covering letter, a description of research experience/projects and three referees contact information.

If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter. You will also be required to complete some initial screening questions.

Closing Date: Until Filled

For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, and possess all the required experience and qualifications should apply.

UHN thanks all applicants, however, only those selected for an interview will be contacted.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity and welcomes all applicants including but not limited to: all religions and ethnicities, LGBTQ2s+, BIPOC, persons with disabilities and all others who may contribute to the further diversification of ideas. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted. network